Three men were arrested with 143.33g of mephedrone worth Rs 14.94 lakh on Saturday, while a fourth suspect is absconding.
The drug was being supplied in areas around Ellis Bridge and Kavi Nhanalal Dalpatram Bridge.
A raid led to the arrests of Faisal Kakuvala and Anish Motiwala in Jamalpur, who led the police to Arif Sheikh in Vatva who allegedly supplied the drug to them.
Police recovered the drugs and filed a case under the NDPS Act.